Senior Laboratory Research Scientist

Job Title: Senior Laboratory Research Scientist (SLRS)

Details of the role: 3-year fixed term (possibly becoming permanent), full-time. Working pattern: Monday - Friday.

Salary: From £39,950 dependent on skills and experience, with benefits

Application closing date: No closing date

About us

The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

The Gutierrez lab is in the research group "Host-pathogen interactions in tuberculosis" and has a long-standing interest in developing novel human induced pluripotent stem cell (iPSC)-based in vitro models of complex disease to study infection and treatment (Pellegrino et al.,2021; Aylan et al., 2023; Bussi et al., 2023). The SLRS position has been created to ensure the successful implementation of projects that aim to develop bioengineered stem cells based cellular systems to better understand lung infection and treatment. Specifically, we are engineering physiologically inspired human lung models combining human (iPSC) technologies with microfluidic devices.

This role is critical to generate tools and perform cell-based experiments, requiring substantial experience in human induced pluripotent stem cell (iPSC) culture, differentiation and reprogramming. Experience in CRISPR/Cas9 genome editing is desirable. You will be part of a diverse and collegial team focused on advancing human iPSC-derived technologies to study infection and treatment. You will provide deep technical knowledge and hands-on expertise in the culture, characterization and differentiation of human iPSCs into lung cells.

What you will be doing

As an SLRS at the Crick, you will:

• iPSC culture and maintenance
• iPSC differentiation and differentiated cell production
• iPSC characterisation
• Somatic cell reprogramming into iPSC
• iPSC gene editing

About you

You will bring

• Extensive experience in long-term iPSC culture, differentiation, and characterization (imaging and flow cytometry).
• Ability to independently propose, design, execute and report on research projects, as well as to work collaboratively with an interdisciplinary research team.
• Proven track record of scientific publications

To see the complete job description, click here .

To see more about team/Group Leader here .

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture!

We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently.

We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world.

We are collegial. We show respect for one another, work cooperatively and support the wider community.

At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email:

To find out more about life at the Crick click here .

What will you receive?

At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

Visas: Applicants for this role will be eligible for sponsorship to work in the UK

Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.

Pension Scheme: Defined contribution pension with employer contributions of up to 16%.

Health & Well-being:

24/7 GP consultation services.

Occupational health services and mental health support programs.

Eye care vouchers and discounted healthcare plans.

Work-Life Balance:

Back-up care for dependents.

Childcare support allowance.

Annual leave purchase options.

Crick Networks offering diverse groups' support, community and inclusive social events.

Perks:

Discounted gym memberships, bike-to-work scheme, and shopping discounts.

Subsidised on-site restaurant and social spaces for team interaction.

Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.