Lead Statistician, Evidera

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Lead Statistician, Evidera

At Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future

Position Overview:

The Lead Statistician works with multi-disciplinary research teams to provide methodological expertise, leadership and strategic support at all stages of projects from planning to completion. This individual provides guidance to junior and middle level staff or works independently on projects requiring advanced statistical analysis, interpretation and dissemination of findings.

This is a fully remote based role.

Essential Functions):

• Statistical Analysis Plan (SAP) Development

  • Drafts SAPs for projects that require use of advanced statistical methodologies

  • Advises junior and middle level staff on methodology and approach on projects requiring use of standard statistical methodologies

  • Reviews and approves SAPs projects that require use of standard statistical methodologies

• Implementation & Interpretation of Analyses

  • Project Lead (including execution of analyses) on project requiring the use of advanced statistical methodologies

  • Provides guidance and advice as needed for junior and mid-level staff on projects requiring use of standard statistical methodologies

• Proposal Writing and Report Preparation

  • Leads proposal development in familiar project-types or takes a supportive role for more complex projects

  • Determines technical approach, reviews proposal drafts and takes responsibility of stats components

  • Gets involved in client discussions

  • Obtains significant levels of repeat business from clients

  • May lead technical response to requests for proposals, generates repeat work and amendments

  • May identify opportunities for new work

  • May advise and peer-review budget

• Communication with internal/external Clients

  • Leads meetings and discussions with clients

  • Acts as an escalation point for client concerns related to the project

  • Communicate effectively and proactively with project teams

  • Ability to work with and delegate to junior and mid-level staff, responsible for deliverable quality and integrity

  • Reviews and supports presentations by more junior staff

• Consulting Expectations

  • Provides on-the-spot problem-solving and consulting in discussions of results

  • Provides methodological expertise within and outside the team

• Methodological Development

  • Contributes to the conceptualization and development of novel/bespoke solutions to meet client project needs

  • Independently investigates the properties, applicability and advantages/disadvantages of both:

    • Methodologies developed by Evidera as bespoke solutions to client projects

    • Newly published methodologies, and seeks senior input when needed

  • May lead the development of parts of tools/macros that improve efficiency of project execution, seeking senior input when needed

  • Provides technical training on the developed tools within HEMA

• Scientific Presence

  • Develops and implements scientific best practices/guidelines, product development/new methods, or deliverable standards

  • Supports external thought leadership through publications and workshops

  • Looks for opportunities to disseminate knowledge

• Financial - Responsible for achieving utilization and proposal and sales target

• Management - Can supervise and mentor junior and middle level staff, involvement in hiring and development of staff, conducting performance reviews.

Education, Professional Skills & Experience

• Bachelors plus 10 years hands-on experience, Masters plus 6 years hands-on experience, or Doctorate plus 3 years hands-on experience in Biostatistics, Statistics, or Related field

• Strong basis in fundamental statistical concepts and methods, and expertise with techniques such as regression analysis (continuous, binary, count data), longitudinal data analysis (mixed effects linear regression), parametric and semi-parametric survival analysis, meta-analysis, indirect treatment comparisons, issues related to missing data, etc.

• Practical experience in standard statistical applications in health economics such as

  • Standard parametric and semi-parametric survival analyses

  • Flexible parametric models (spline, piecewise)

  • ITC methods (Bucher, network meta-analyses NMA , matching-adjusted indirect comparisons MAICs , simulated treatment comparisons)

  • Country-specific utility analyses to inform CEMs

• Familiarity with complex methods, including:

  • Projecting incomplete survival data using Bayesian parametric survival models with informative priors

  • Adjustment for treatment switching (rank preserving structural failure time, inverse probability of censoring weighting, two-stage estimation)

  • Mixture cure models

  • Multi-state models

  • Multilevel network meta-regression and fractional polynomial NMA

  • Surrogacy analyses

• Strong statistical programming skills with standard software, including R and/or STATA/SAS

• Ability to communicate analysis plans and results to clients or colleagues who may have limited background in statistics

• Scientific visibility in terms of authorship of peer-reviewed publications, podium presentations and posters at conferences

Personal Skills & Competencies

• Demonstrates sound professional judgment in analyzing, responding to, and resolving enquiries, issues and escalations

• Work well in a team as well as independently and be able to take leadership role with regard to methodological elements in projects.

• Demonstrated ability to communicate and document information effectively in written English, including the ability to produce reports, documents, emails and other written pieces which are well-organized, free from errors, and are appropriately adjusted to the characteristics and needs of the audience.

• Able to create, communicate, and manage effective project plans that support the delivery of overall project objective(s); to identify, manage and guide project team members; to monitor and report on progress in an organized fashion; and to deliver the required results.

Benefits

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. with PPD, part of Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.

Apply today!

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.